Long-term outcome in couples with unexplained subfertility and an intermediate prognosis initially randomized between expectant management and immediate treatment Inge M. Custers 1,*, Minouche M.E. van Rumste2, Jan Willem van der Steeg1, Madelon van Wely 1, Peter G.A. Hompes 3, Patrick Bossuyt 4, Frank J. Broekmans 5, Cees N.M. Renckens 6, Marinus J.C. Eijkemans 7, Thierry J.H.M. van Dessel 8, Fulco van der Veen1, Ben W.J. Mol 2, Pieternel Steures 1, and CECERM9
In couples with unexplained subfertility and an intermediate prognosis of natural conception, initial EM for 6 months results in a considerable cost-saving with no delay in achieving pregnancy or jeopardizing the chance of pregnancy. Further comparisons between aggressive and milder forms of ovarian stimulation should be performed DOI: 10.1093/humrep/der389
Human Reproduction, Vol.33, No.6 pp. 1130–1140, 2018 Advanced Access publication on April 6, 2018 doi:10.1093/humrep/dey082 ORIGINAL ARTICLE Reproductive endocrinology
Follicle growth and endocrine dynamics in women with spontaneous luteinized unruptured follicles versus ovulation S. T. Bashir1 , A. R. Baerwald2 , M. O. Gastal1 , R. A. Pierson2 , and E. L. Gastal1,* 1 Department of Animal Science, Food and Nutrition, Southern Illinois University, Carbondale, IL 62901, USA 2 Department of Obstetrics and Gynecology, College of Medicine, University of Saskatchewan, Royal University Hospital, Saskatoon, Saskatchewan, S7N 0W8, Canada
Objective: To review whether detailed videolaparoscopic evaluation of so called unexplained infertility can find out certain causes and laparoscopic corrective techniques can alleviate them. Methods: From 1998 to 2007, 1726 cases of unexplained infertility were investigated by laparoscopy at Repose Fertility Clinic, Kolkata. 846 minor tubal defects were detected. Results: According to our observation tubal defects were classified into six categories. Most of them belonged to combined aetiology. Conclusion : Different laparoscopic surgical techniques to restore structural and functional integrity of fallopian tubes may be useful in achieving pregnancy in many cases of so called unexplained infertility...
Current methods of tubal patency assessment. Fertility and Sterility Vol. 95, No. 7, June 2011 2171 doi:10.1016/j.fertnstert.2011.02.054 Copyright ª2011 American Society for Reproductive Medicine, Published by Elsevier IncRhiana D. Saunders, M.D., James M. Shwayder, M.D., J.D., and Steven T. Nakajima, M.D. Department of Obstetrics, Gynecology and Women’s Health, University of Louisville, Louisville, Kentucky
Should a hysterosalpingogram be a first-line investigation to diagnose female tubal subfertility in the modern subfertility workup? Chou Phay Lim1, Zaid Hasafa 1, S. Bhattacharya 2, and A. Maheshwari 3,* 1 Obstetrics and Gynaecology
Tubal assessment is an integral part of female fertility evaluation. While diagnostic laparoscopy is gold standard, it is not suitable to be used as a screening test. Hysterosalpingogram (HSG) has been advocated as first-line investigation historically. With advances in diagnostics, more tests are available, such as hysterosalpingo contrast sonography (HyCoSy) and Chlamydia antibody titre (CAT) are available. The CAT test is much cheaper, less invasive and can be performed at any time during the cycle. The CAT test can also be used as a means of identifying which patients need further evaluation. HyCoSy has same diagnostic accuracy as HSG, without exposing women to radiation. We argue that HSG is out of date and has no place in a modern infertility evaluation. We also suggest a pathway (based on history, clinical and ultrasound evaluation) for investigations to screen for and diagnose tubal pathology...